WISE Health: Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults


WISE Health: Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults

Drew Sayer, Ph.D.

Assistant Professor, Medicine, Family & Community Medicine, University of Alabama at Birmingham

Primary aim of study: Determine the feasibility and preliminary effectiveness of a SMART to compare weight-focused and weight-neutral biobehavioral interventions for improving cardiometabolic health. Participants receive 6-months of either weight-focused (i.e., behavioral weight loss) or weight-neutral (not emphasizing weight loss) health coaching. Sub-optimal responders to initial strategies will be re-randomized to either an intensified lifestyle intervention or PCP-led enhanced medical management.

Diseases or conditions being studied: Overweight or obesity with concomitant prehypertension/hypertension, prediabetes/diabetes, and/or dyslipidemia
Communities of Focus: Black adults with overweight or obesity and weight-related cardiometabolic conditions residing in the Birmingham metro area
Study Sites: Birmingham, AL
Study Population: Black adults with obesity and associated cardiometabolic conditions in the Birmingham, Alabama (AL) metro area
Community or non-academic partners: YMCA of Greater Birmingham
Primary outcome: Clinical trial/SMART feasibility, treatment acceptability & credibility, estimates of treatment effect sizes and variances
Outcome measures collected at: Baseline, week 8, and week 26
Levels of action:
1) Individual level (health behaviors),
2) Community (access to education, parks, gyms, & recreation)

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