Forge AHEAD Center Announces Fourth Cohort of Scholars Focused on HIV

Forge AHEAD Center Announces Fourth Cohort of Scholars Focused on HIV

The Forge AHEAD Center (FAC) is delighted to introduce the recipients of its pilot funding for the fourth cohort, with a specific focus on HIV prevention and management in the Deep South.

These four early-stage investigators were selected for their groundbreaking research aimed at addressing critical public health issues related to HIV.

Their work aligns perfectly with the Forge AHEAD Center’s mission of reducing health disparities and fostering healthier communities through innovative research endeavors.

Introducing the Fourth Cohort Scholars

We are honored to recognize the following outstanding researchers, whose projects all center around improving health outcomes for people living with HIV:

Kristen Allen-Watts, Ph.D. headshot

Kristen Allen-Watts, Ph.D.
Assistant professor at the University of Alabama at Birmingham

Project: “Peer MODELS: (Managing a Community-based HIV, Diabetes, and pain intervention that Encourages healthy Living and provides Support), for PWH and T2D in the setting of chronic pain”

Headshot of Dr. Donald Gerke

Donny Gerke, Ph.D.
Assistant professor at the University of Alabama at Birmingham

Project: “Facilitated Stable Housing as a Strategy for Uptake and Sustainment of Evidence-Based HIV and Cardiometabolic Medicine in People with HIV”

Headshot of Gravett

Matt Gravett, M.D.
Assistant professor at the University of Alabama at Birmingham

Project: “Laying the Foundation for PrEP in Urgent Care Settings”

Xie headshot

Rongbing Xie, DrPH
Assistant professor at the University of Alabama at Birmingham

Project: “Enhancing Recruitment and Retention for Black Females with HIV: Identifying Barriers, Facilitators, and the Role of Social Determinants for the Willingness to Participate in the HEALTH Study”

Empowering Scholarly Success

The Forge AHEAD Center is committed to fostering a supportive environment for our scholars. Each recipient will receive both strategic guidance and mentorship throughout their research journey. This comprehensive approach empowers them to translate their visions into impactful research that holds the potential to make a significant contribution to reducing HIV-related health disparities across the Deep South.

Investing in the Future of HIV/AIDS Health

By funding these groundbreaking projects, the Forge AHEAD Center demonstrates its unwavering dedication to advancing health equity and improving the well-being of individuals living with HIV across the South. We are confident that the work of our fourth cohort will have a lasting positive impact on our communities.

Stay Connected!

For more details about the scholars and their research endeavors, please visit this page. We are actively seeking talented investigators for upcoming funding cycles. Early-stage investigators interested in applying for pilot awards are encouraged to visit our website for application guidelines and deadlines. The RFA for Cohort 5 is currently open, with Letters of Intent due on June 25, 2024.

Katie Ellison’s Journey: Triumph, Mentorship, and the George Bray Obesity Research Award

Katie Ellison’s Journey: Triumph, Mentorship, and the George Bray Obesity Research Award

Katie M. Ellison, M.S., a doctoral student at the University of Alabama at Birmingham (UAB), is on a remarkable journey that blends personal struggles with professional triumphs. This journey will soon be celebrated on the grand stage of the Nutrition 2024 conference in Chicago, IL, where she will receive the prestigious George Bray Obesity Research Student Award.

This award not only recognizes her groundbreaking work but also underscores the vital mentorship of FAC Core Project Principal Investigator Drew Sayer, Ph.D., whose guidance has been essential in her journey.

The Mentor’s Influence

Ellison speaks about the profound impact Sayer has had on her career. “Dr. Sayer has significantly shaped my approach to research and my professional growth,” she shared. “One of the most valuable lessons I’ve learned from him is the importance of perseverance and curiosity in scientific research.” Sayer, who found his passion for public health early on, said, “Even during my undergraduate years, I was more drawn to the public health implications of healthy eating and physical activity than just sports performance. Obesity research felt like a natural fit.”

Ellison’s enthusiasm and commitment have been evident from the start. “Katie has that ‘it factor’ that’s hard to describe but easy to recognize. Her enthusiasm for this work is infectious, and her genuine desire to improve lives brings a unique perspective,” Sayer noted.

Katie Ellison (right) with her mentor Drew Sayer, Ph.D. (second from right), and colleagues at a research presentation.

A Personal Motivation

Ellison’s passion for obesity research is deeply personal, stemming from her own battles with weight. “I was inspired to pursue a career in nutrition sciences and obesity research because of my personal journey with weight loss and the challenges I faced,” she explained. “I have seen firsthand the profound impact that obesity can have on individuals and their families. This experience has fueled my determination to help others overcome similar struggles.”

Did You Know?

Dr. George Bray was the founding Executive Director of the Pennington Biomedical Research Center, a Forge AHEAD partner institution, and is internationally recognized for his research in obesity. The George Bray Obesity Research Student Award, endowed by Dr. Bray and his wife Marilyn, continues to honor his legacy by recognizing outstanding student research in obesity.

Award and Research Focus

Receiving the George Bray Obesity Research Student Award is a pivotal milestone for Ellison. “I was incredibly honored and excited to learn that I was receiving the George Bray Obesity Research Student Award. I believe my research stood out because it addresses a critical gap in understanding the behavioral aspects of obesity,” Ellison said.

Her work aims to uncover strategies that can improve health outcomes for individuals struggling with obesity. “My research aims to understand how specific behavioral strategies can improve weight loss outcomes and overall health in individuals with obesity. My own journey taught me the importance of sustainable lifestyle changes, and I hope this work will contribute to more effective treatment protocols for obesity,” she elaborated. Her work is not just about data; it’s about changing lives.

 

Sayer highlighted the significance of this achievement, saying, “George Bray is a pioneer in obesity research and receiving an award bearing his name is a tremendous accomplishment for Katie and a testament to the quality of her work. There is a lot of interest in the concept of ‘precision nutrition’ in obesity research treatment. I hope that this award signals a growing interest and emphasis on innovative experimental designs that can bridge the translational gap between traditional clinical research and the delivery of adaptive and personalized care to people living with obesity.”

Future Aspirations

Looking ahead, Ellison has clear goals. “Following this award, my aspirations are to further explore innovative behavioral interventions that can be integrated into clinical practice. I plan to build on my current research to develop comprehensive treatment strategies that address the multifaceted nature of obesity.” Her vision is one of a healthier future for all, where effective treatment strategies can lead to lasting health improvements.

Ellison’s recognition with the George Bray Obesity Research Student Award is a testament to her perseverance, the mentorship she received, and her dedication to making a difference. Her work, guided by Sayer, exemplifies the spirit of collaboration and innovation at Forge AHEAD. As Ellison continues her journey, her contributions are set to shape the future of obesity treatment, offering hope and better health outcomes.

Katie Ellison’s story is one of courage, determination, and the transformative power of mentorship. It highlights the importance of resilience, curiosity, and the incredible impact of one person’s dedication.

“Dr. Sayer has significantly influenced my approach to research and my professional development. One of the most valuable lessons I’ve learned from him is the importance of perseverance and curiosity in scientific research.” – Katie Ellison

Our Scholars’ stories: Lai tests virtual reality gaming exercise benefits at a local high school for youth with disabilities

Lai tests virtual reality gaming exercise benefits at a local high school for youth with disabilities

Byron Lai, Ph.D., assistant professor in the Division of Pediatric Rehabilitation Medicine at the University of Alabama at Birmingham, is researching a new way to help children with disabilities stay healthy.

Lai’s project, “Preliminary implementation and development of an enjoyable virtual reality exercise program for the prevention of cardiometabolic disease among children with disabilities in school settings,” allows participants to do their rehabilitation exercises through video games.

The goal is to see if virtual reality gaming and exercise can help children with disabilities avoid health problems related to their heart and metabolism.

Video games that improve health

“The purpose of the project is to work with a community engagement group to develop a protocol for implementing a research-tested therapeutic exercise program for youth with disabilities at a high school,” says Lai.

Lai is testing this exercise program in a special physical education class at a high school. He wants to see what impacts the program has on exercise-related outcomes like physical strength and how well the heart and lungs work.

A total of 12 children will be included in the study to start. This project will include a Community Engagement Group of three members from the school where the intervention will be delivered, a child with cerebral palsy, their caregiver, and a Special Physical Education teacher.

“The project is being supported by school staff and, most importantly, being delivered by a young man with a physical and cognitive disability, who was a student at the high school,” says Lai.

“Should this project be successful, it could open up a means for employment for youth with disabilities, when the project is delivered on a national scale. This project is also the first collaborative project with the community by the Division of Pediatric Rehabilitation Medicine at UAB and Children’s Hospital of Alabama, which could open doors for further projects and services.”

Lai says the group will meet regularly to talk about how the program is delivered and what changes might be needed.

If this study shows the exercise program works well, Lai will use the study results to apply for additional funding to conduct a larger study to confirm if it really helps kids with disabilities stay healthy. “This project will serve as a model for helping other schools in a larger trial,” he says.

The findings of this study will inform an upcoming NIHR01 application to confirm the effectiveness of the virtual reality exercise program on cardiometabolic health among children with physical disabilities.

Our Scholars’ stories: Cardozo explores the link between PCOS and cardiovascular disease

Cardozo explores the link between PCOS and cardiovascular disease

Licy Yanes Cardozo, M.D., associate professor at the University of Mississippi Medical Center, is delving into the interesting connection between Polycystic Ovary Syndrome (PCOS) and cardiovascular disease.

PCOS is a common hormonal disorder affecting women of reproductive age, characterized by high levels of male hormones and irregular menstrual cycles.

While the exact cause of PCOS remains unknown, it’s evident that women with this condition face an increased risk of cardiovascular issues. Cardiovascular disease is the leading cause of death in women in the U.S.

Notably, Black/African American women with PCOS are at an even higher risk of cardiovascular complications, though the reasons for this racial disparity are not fully understood. Social determinants of health (SDoH), such as education, employment, income, and food security, could play a significant role.

Cardozo’s why

“Women’s health suffers from numerous inequities, especially in the South,” Cardozo says. “As a woman and a mother of two girls, I am passionate about using my voice, knowledge, and energy to improve cardiovascular health among women.”

Moreover, Cardozo states: “cardiovascular diseases are the leading cause of death among women, thereby this is a key area of research. I hope that the findings of our research make a positive impact on the community, filling the multiple gaps that exist in our understanding of cardiovascular diseases in women, especially among African Americans.”

The project plan

Cardozo’s team aims to investigate how SDoH contribute to cardiovascular risk factors in Black/African American women compared to white women with PCOS, and how this correlates with hormonal imbalances and dysregulation of factors affecting blood pressure and metabolism.

As a physician-scientist, Cardozo says she seeks to determine whether SDoH are responsible for the elevated cardiovascular risk observed in Black/African American women with PCOS.

Her study will utilize questionnaires to assess SDoH, analyze blood samples related to cardiovascular disease, and examine obesity as a contributing factor.

The findings from this research endeavor are expected to provide deeper insights into effective treatments for managing cardiovascular disease in Black women with PCOS.

Cardozo anticipates that this study will lead to improved strategies for addressing cardiovascular issues in women, particularly among those who face disproportionate risks, such as Black/African American women with PCOS.

Our scholars’ stories: Myers explores a weight loss intervention at the intersection of food insecurity and excess body weight in women

Our scholars’ stories: Myers explores a weight loss intervention at the intersection of food insecurity and excess body weight in women

Candice A. Myers, Ph.D., M.S., assistant professor of Population and Public Health Sciences at Pennington Biomedical Research Center at LSU and director of the Social Determinants and Health Disparities Laboratory, is pioneering a project aimed to help women who experience both food insecurity and excess body weight.

Her project, TARGETing Health Weight Loss in the Context of Food Insecurity Pilot and Feasibility Trial II, will test a weight loss intervention for women with excess body weight who are experiencing food insecurity. Food insecurity, or the lack of sufficient food in both quality and quantity for an active and healthy life, is a pressing health issue in the United States, with over 18% of adults being food insecure.

“Food insecurity is a risk factor for multiple chronic diseases, including obesity,” says Myers.

“Importantly, both food insecurity and excess body weight are significantly linked in women. Research efforts are needed to address and mitigate this health disparity.”

Myers’ “Why”

Myers says that as a sociologist, she has actively pursued an academic health researcher career by seeking a deeper understanding of the “concomitant influence” of sociological and biological mechanisms that shape disparate health outcomes.

“A key theme that underlies my entire research career to date is an explicit focus on disparities, socioeconomic disparities during my graduate training, and health disparities during my postdoctoral training.”

For Myers, postdoctoral training provided an opportunity to research obesity, where she discovered food insecurity as a pressing health issue, particularly about obesity.

“Calling upon my graduate work in both food stamp program participation and poverty, I focus on food insecurity as a risk factor for poor health and source of health disparities.”

A better future for women experiencing food insecurity

Myers’ project will provide novel data on a weight loss intervention tailored for women who face the dual burden of food insecurity and body weight, which impacts their overall health and quality of life.

The TARGET intervention is being developed using data from a sample of key stakeholders from the local Baton Rouge community: women who experience both food insecurity and obesity. In focus groups, they will offer information on their wants and needs for weight loss.

The goal of the current pilot study is to test the TARGET intervention. This study will enroll 15 food-insecure women (ages 18-65) with obesity, where all participants receive the tailored weight loss intervention. The 12-week intervention includes weekly individual intervention sessions. The primary outcome will be a change in body weight across 12 weeks.

Participants will receive scales in-home to obtain weekly body weight in tandem with weekly intervention sessions. Secondary outcomes will be assessed using validated questionnaires.

Researchers, public health officials, and local community members will also benefit from this preliminary work by laying the groundwork for future studies.

This study has significant public health implications by addressing psychological mechanisms that can be targeted to mitigate the adverse relationship between food insecurity and obesity and reduce health disparities in vulnerable populations.

Our Scholars’ stories: Worthington revolutionizes maternal health through innovative nutrition programs

Our Scholars’ stories: Worthington revolutionizes maternal health through innovative nutrition programs

 

Camille Worthington, Ph.D., assistant professor in the Department of Medicine at the University of Alabama at Birmingham (UAB), is spearheading a groundbreaking initiative to transform maternal health through innovative nutritional interventions.

Her project, “Use of Home-Delivered Meals to Manage Cardiometabolic Health during Pregnancy among Predominantly Black, Low-Income Women in Alabama,” focuses on the critical juncture of pregnancy, diet, maternal well-being, and birth outcomes among Medicaid-eligible pregnant individuals.

Worthington’s “Why”

At the heart of Worthington’s initiative lies a profound purpose—to resolve the disparities prevalent in healthy eating and appropriate pregnancy weight gain that contribute to unequal risk of poor pregnancy outcomes, such as high blood pressure, particularly among marginalized communities.

“The U.S. and Alabama have some of the highest rates of pregnancy complications, poor pregnancy outcomes, and mom and baby death related to pregnancy,” Worthington explains. “Good nutrition is an important part of a healthy pregnancy, but not everyone has the ability to afford or access a healthy diet.”

Worthington explains that neighborhoods with more Black/African American residents and more low-income households have more fast-food restaurants, less grocery stores, and fewer healthy food options. These circumstances contribute to poor outcomes during pregnancy.

A staggering 70% of pregnant women exceed recommended intakes of added sugars, sodium, and saturated fats. Additionally, more than half gain excess weight during pregnancy, risking their and their babies’ health.

Transforming outcomes through food delivery

“The purpose of my project is to see if providing pregnant moms who are Medicaid-eligible with ten free healthy meals delivered right to their homes each week during their pregnancy helps them eat healthier, gain the right amount of pregnancy weight, have less stress, and if it is a service that they like,” says Worthington.

She envisions a transformative impact on the community by providing access to healthy meals.

“Healthy meal delivery can support healthier pregnancies, which supports healthier babies, and ultimately healthier communities,” she says.

“Long-term, we hope to show that providing pregnant people with healthy meals improves pregnancy outcomes and saves insurance companies money by preventing moms and babies from having pregnancy complications and having to stay in the hospital.”

Worthington explains that pregnant individuals eligible for Medicaid are participants in the program. Health care providers, community organizations supporting expectant mothers, and insurance providers are stakeholders in broader implementation.

Moving towards change

“We want healthy meal delivery to become a covered health care service to support all moms’ ability to eat healthy and have a healthy pregnancy.”

Worthington passionately emphasizes the intrinsic link between a balanced diet, stress reduction, and improved health outcomes for both mother and baby, paving the way to address the prevailing disparities in maternal healthcare across the U.S.

“Overall, a better diet, healthier pregnancy weight gain, and lower stress can improve health outcomes for mom and baby and could help to overcome the unequal rates of pregnancy complications that we see in the U.S.,” she says.

Worthington’s visionary initiative serves as a beacon of hope, steering academia, health care providers, and policymakers toward a paradigm shift in maternal health, advocating for a future where access to nutritious meals becomes an inalienable right for every expectant mother.